Bern researchers develop non-contagious coronavirus in the laboratory

Bern researchers develop non-contagious coronavirus in the laboratory
Bern researchers develop non-contagious coronavirus in the laboratory
  • 1/11

    Volker Thiel’s team has made a breakthrough in corona research.

  • 2/11

    The researchers were able to remove the spike gene (red in the picture). The virus is therefore harmless and can no longer cause chains of infection.

  • 10/11

    There is great interest in research in Bern abroad. “We have already received a number of inquiries from the USA and Europe.”

  • 11/11

    For a year, Volker Thiel’s team (pictured) worked with scientists from Rockefeller University in New York to develop this variant using a molecular clone.

Researchers from Bern land the latest Corona coup! They managed to clone the virus and develop a non-contagious variant in the laboratory. This is an important breakthrough for science.

Specifically, the team led by Volker Thiel (54), head of the virology department at the Institute for Virology and Immunology (IVI) and professor at the University of Bern, was able to remove the spike gene. This means that the virus can no longer dock onto other cells and cause chains of infection. “We kind of pulled the tiger’s teeth,” Thiel says of “Tele Bear”.

For a year, Thiel’s team worked with scientists from Rockefeller University in New York to develop this variant using a molecular clone, explains Volker Thiel to Blick.

No more high-security laboratories

A big leap for corona research. Because now working with the virus no longer has to take place under strict security measures. The virologist on Blick: “There are not very many high-security laboratories worldwide and that limits research on Sars-CoV-2. With the harmless virus, ‘normal’ laboratories can now also carry out studies. “

In a high-security laboratory, it was not possible to install large and highly sensitive devices due to reasons of space, among other things. However, these are of great importance when investigating mutations. Thanks to the Swiss Corona clone, this is now theoretically possible. “However, you first have to apply for work at a lower security level and then the authorities carefully examine it,” says Thiel.

There is great interest in research in Bern abroad. «We have already received a number of inquiries from the USA and Europe. The system can for example be made available by means of the cloned DNA. This then enables the other laboratories to produce the harmless variant themselves. “

Developing Effective Medicines

The new Corona doppelganger allows researchers to carry out simple and harmless examinations. Among other things, the amount of antibodies produced by a vaccine can be determined in this way.

And this can also accelerate the development of corona drugs. “For example, you can observe the multiplication of the harmless virus in a cell and compare whether an inhibitor inhibits the multiplication,” says Thiel. An inhibitor can be a drug or a precursor, explains the immunologist.

In theory, there are now many options open to scientists. However, one thing is not possible with the Swiss clone. “You can examine almost anything with the harmless virus that you can examine with the dangerous virus. Except, for example, the spread of the virus through several cells. That is precisely the safety aspect that no more infectious virus can escape from infected cells, ”he says.

Zug Cantonal Doctor Rudolf Hauri: “We hope that decisions will be made soon with regard to the booster vaccination”(02:04)

Source

Bern researchers develop noncontagious coronavirus laboratory

 
For Latest Updates Follow us on Google News
 

PREV Economy is pushing for the end of lockdown – ooe.ORF.at
NEXT Woman found dead in cellar in Vienna-Brigittenau – crime