A real social and professional handicap, migraine affects 15% of the world population. Severe headaches, difficult to cure. “Currently, in the preventive treatment of migraine, patients are only offered antiepileptics, antidepressants, beta blockers for blood pressure, per se things that are not migraine specific at all and may also have side effects“, recalls Rémi Shrivastava, doctor in neurosciences and president of the pharmaceutical laboratory Naturveda, based in Issoire.
He was interested in the effects of plants, in particular feverfew in the treatment of this particular pain. The entrepreneur then embarked on a thesis at Clermont Auvergne University within Neuro-dol, a research unit linked to Inserm which works on pain and in particular the treatment of migraine.
Rémi Shrivastava studies the active principles of plants and how to preserve them. “A plant will be of quality from the moment it has grown in such an environment, under certain conditions, we also study its methods of extraction, storage …“, all this to ensure its properties.”All these questions must be asked upstream, otherwise we end up with a product that has no effectiveness.”
A nasal spray for migraine prevention
After 7 years of research and clinical trials, the Issoirian laboratory today manufactures and markets a nasal spray and capsules, based on plants. “Stopping a migraine attack when it is triggered is extremely complicated “, specifies Rémi Shrivastava who has developed a preventive treatment over the long term. “When you use natural active ingredients, you have to accept that it takes time to be effective. It is a preventive treatment that will prove itself after 4 to 6 weeks..”
Its product, Mig Spray, is currently distributed in 500 pharmacies in France and sold for 15 euros. The Issoirian company now hopes to distribute it in Europe.